The effect of Vitamin D supplementation on breast cancer risk

Abstract The clashing of vitamin D appurtenance on doorknocker pubic louse prevention and diminishment has conk out a matter of sustained controversy. This analyze proposes to enforce a combination Post-Positivism approach to assess the practice. With emerging studies both upholding and decrying the readiness of Vitamin D in sexual relation to depreciator crabmeat, there is a need pursue this study in order to clarify the potential. psychiatric hospital doorknocker crab louse and vitamin D supplementation have become a substantial topic of debate as a drive to find a solution continues. This study fills a gap in existing look into by assessing what impact the addition of Vitamin D has on the prevention and diminishment of Breast Cancer.1.1 BackgroundThe efficacy of Vitamin D supplementation in order to prevent or diminish Breast Cancer has become a matter of sustained debate. The Mohr, Gorham and Alcaraz (2012) study argues that there is a direct benefit to the decr ement of titmouse crabby person by adding Vitamin D both before and after a malignant neoplastic disease diagnosis. Others rear the impact of Vitamin D on Breast Cancer as only negligible (Prentice, Prettinger and Jackson 2013). Still others cite the early stage of research as an obstacle to fully embracing the value of Vitamin D (Yin, Grandi and Raum 2010). Yet, go on studies link Vitamin D and the method acting of ingestion as a pivotal issue (Prentice et al 2013). The purpose of this study would be to further determine the role of Vitamin D in relation to chest of drawers cancer in women.1.2 Aims and ObjectivesIn this section, the research aims, objectives, and research questions ordain be outlined. Firstly, the aim of this research is as followsThe following research objectives have been determinedWhat is the effect of vitamin D supplementation on breast cancer peril of exposure What is the vitamin D status, determined by 25-OH vitamin D levels, among women diagno sed with breast cancer 1.3 explore QuestionsThe research question isWhat are the cognize associations with Vitamin D supplementation and breast cancer What are the key factors that have been impacted by Vitamin D supplementation of cancer Do the means of Vitamin D ingestion have an impact on military strength What is the potential emerging research teaching 2 Literature Review 2.1 Factors that contribute to Breast CancerDeficiencies in all forms have long been credited with the increasing the probability for cancer of all varieties (Pearce and Cheetham 2010). Factors including the lack of Vitamin D have been linked to breast cancer diagnosis in women (Chung, Lee and Terasawa 2011). With lifestyle choices and long-term habits acting a pivotal role in a cancer diagnosis, the impact of a single broker is debateable (Brasky, Lampe and Potter 2010). Diseases including Rickets and osteomalacia are directly tied to vitamin D deficiency, making a breast cancer link plausible (Pearce e t al 2010). The presence of or lack of vitamins are argued to impact a breast cancer diagnosis.2.2 Vitamin D and Breast Cancer supplementation in WomenA wide array of professionals ranging across clinical applications, autoimmunity, cardiology and cancer fields agree that the Vitamin D supplementation is a benefit to the effort to increase breast prevention efforts (Souberbielle, Jeanjacques Body and Lappe 2010). Yet, Prentice et al (2013), while maintaining the moderate value of the supplementation practice, argue that the reduction in breast cancer occurrence due to this factor is only suggestive, not conclusive.2.3 Vitamin D and Breast Cancer Prevention OptionWolff and Guiliano (2011) have found that Vitamin D as a supplement is superior to a dietary intake of vitamin D. This study charts a correlation surrounded by the incidents of breast cancer prevention and the dietary method of vitamin intake. It is insufficient to rely on any single indicator in as a prevention mechanis m (Thacher and Clarke 2011). Further, the benefits of vitamin D are only at the observational stage and cannot be fully accredited (Ibid).2.4TrendsThe combination of Calcium/Vitamin D is providing an avenue for research towards a diminished rate of breast cancer (Bolland, Grey, Gamble and Reid 2011). Conversely, Brunner, Wactawski-Wende and Cann (2011) illustrate that there is no substantial reduction in breast cancer among their studies participants employing this combination.3. Methodology The methodology focuses on an explanation of the approaches consideredWhat is the effect of vitamin D supplementation on breast cancer risk What is the vitamin D status, determined by 25-OH vitamin D levels, among women diagnosed with breast cancer3.1 ApproachPositivism, quantitative method, provides solutions resting in math, producing empirical information (Yin 2003). Interpretivism or qualitative uses the interpretive approach utilizing instruments like coding. Post-Positivism, a combinati on of the two is best fit to determine the impact of Vitamin D supplementation on breast cancer in women (Bryan and Bell 2007). twain inductive and deductive approaches were considered. Bryan et al (2007) view both approaches as connected with distinct elements, but the conjunctive are not fixed. Therefore settled the use of a mixed method or post-positivism method was chosen as the best approach.3.2 Research StrategyThis study will collect and analyse empirical selective information (Biggam 2012). The utilization of both primary and secondary research material will provide depth and of import clarity to the study (Yin 2003). The empirical research in this study deals with an in-depth review of breast cancer cases, survivors and applicable medical professionals. Primary data will be accumulated through the creation and utilization of a survey directly transmitted to breast cancer survivors and oncological professionals (Ibid). Prior and existing case studies will be evaluate d utilizing secondary sources alongside the application of a primary source survey issued to the breast cancer survivors and members of the oncologist community (Yin 2003). This research strategy is best suited to facilitate a well rounded military rating of issues that promote various perspectives in order to gain a comprehensive understanding of the link between Vitamin D supplementation and breast cancer (Lock, Silvermand and Spirduso 2010).3.4 Data Collection Methods and InstrumentsThe collection methods used in this study werePrimary data using Surveys from survivors and medical professionals (Saunders et al 2007). Secondary breast cancer data via ledger and peer reviewed articleThe primary disadvantages rest in the limited capacity to check answers or take aim further details. Further, obtaining primary data may be very high (Yin 2003).7. ReferencesBiggam, J. (2012) Succeeding with Your Masters Dissertation. 2nd ed.Berks. McGraw-HillBoll, Grey, A., Gamble, G. and Reid, I. 2 011. Calcium and vitamin D supplements and health outcomes a reanalysis of the Womens Health Initiative (WHI) limited-access data set. The American journal of clinical nutrition, 94 (4), pp. 11441149.Brasky, T., Lampe, J., Potter, J., Patterson, R. and White, E. 2010. Specialty supplements and breast cancer risk in the VITamins And Lifestyle (VITAL) Cohort. Cancer Epidemiology Biomarkers & Prevention, 19 (7), pp. 16961708.Brunner, R., Wactawski-Wende, J., Caan, B., Cochrane, B., Chlebowski, R., Gass, M., Jacobs, E., Lacroix, A., Lane, D., Larson, J. and Others. 2011. The effect of calcium plus vitamin D on risk for invasive cancer results of the Womens Health Initiative (WHI) calcium plus vitamin D randomized clinical trial. Nutrition and cancer, 63 (6), pp. 827841.Bryan and Bell, (2007)Buisness Research Methods Oxford. University PressChung, M., Lee, J., Terasawa, T., Lau, J. and Trikalinos, T. 2011. Vitamin D with or without calcium supplementation for prevention of cancer and fra ctures an updated meta-analysis for the US Preventive function Task Force. Annals of Internal Medicine, 155 (12), pp. 827838.Locke L. F., Silverman S J and Spirduso, W, W (2010, pg 198) Reading and Understanding Research. tertiary ed.Mohr, S., Gorham, E., Alcaraz, J., Kane, C., Macera, C., Parsons, J., Wingard, D. and Garl. 2012. Does the evidence for an inverse relationship between serum vitamin D status and breast cancer risk satisfy the Hill criteria?. Dermato-endocrinology, 4 (2), pp. 152157.Pearce, S., Cheetham, T. and Others. 2010. Diagnosis and management of vitamin D deficiency. Bmj, 340 p. 5664.Prentice, R., Pettinger, M., Jackson, R., Wactawski-Wende, J., Lacroix, A., Anderson, G., Chlebowski, R., Manson, J., Van Horn, L., Vitolins, M. and Others. 2013. Health risks and benefits from calcium and vitamin D supplementation Womens Health Initiative clinical trial and cohort study. Osteoporosis International, 24 (2), pp. 567580.Serrano, J., De Lorenzo, D., Cassanye, A., Mart In-Gari, M., Espinel, A., Delgado, M., Pamplona, R. and Portero-Otin, M. 2013. Vitamin D receptor BsmI polymorphism modulates soy intake and 25-hydroxyvitamin D supplementation benefits in cardiovascular disease risk factors profile.Genes & nutrition, 8 (6), pp. 561569.Souberbielle, J., Body, J., Lappe, J., Plebani, M., Shoenfeld, Y., Wang, T., Bischoff-Ferrari, H., Cavalier, E., Ebeling, P., Fardellone, P. and Others. 2010. Vitamin D and musculoskeletal health, cardiovascular disease, autoimmunity and cancer Recommendations for clinical practice.Autoimmunity reviews, 9 (11), pp. 709715.Thacher, T. and Clarke, B. 2011. Vitamin D insufficiency. 86 (1), pp. 5060.Yin, L., Gr, I, N., Raum, E., Haug, U., Arndt, V. and Brenner, H. 2010. Meta-analysis serum vitamin D and breast cancer risk. European Journal of Cancer, 46 (12), pp. 21962205.Yin, R. 2003. Case study research. curtilage Oaks, Calif. Sage Publications.Pallant, J. (2010) SPSS8. Gantt Chart